Dr. Ming Wang is Founder, President and CEO of Phanes Therapeutics, Inc. based in San Diego. The company focuses on drug discovery and development to treat cancer and metabolic complications. Ming was formerly Vice President and Disease Area Leader of Diabetes/Metabolism in Janssen, the pharmaceutical sector of Johnson & Johnson, with global responsibility for the diabetes portfolio (from discovery stage to phase 2). In this role, he was responsible for setting strategies for internal innovation and external partnerships, making investment decisions and building a portfolio of assets for disease treatment and prevention. Under his leadership, J&J built a strong pipeline of metabolic assets ranging from discovery stage programs to clinical assets. During his tenure at J&J, Ming’s team built many external partnerships with biotech companies and academic institutions. Ming was also the champion in formulating a strategy for NASH (non-alcoholic steatohepatitis) and other metabolic disease areas for the group. Previously, Ming was Executive Director and Head of Diabetes Research at Amgen where he headed a group of ~50 scientists located in Amgen’s headquarter (Thousand Oaks) and San Francisco, working on developing novel therapies for metabolic diseases. Before joining Amgen, Ming championed drug discovery programs in cardiovascular and metabolic diseases and managed corporate partnerships in Parke-Davis, Pfizer and Pharmacia.
Ming served on multiple advisory boards, including the Scientific Advisory Board (SAB) of Amgen Ventures. He is a frequent organizer and speaker of biotech and pharma conferences and has 59 publications and a book entitled “Metabolic Syndrome: underlying mechanisms and drug therapies” (publisher: John Wiley & Sons, Inc.). He is an Associate Editor of Frontiers in Experimental Pharmacology and Drug Discovery. He holds a PhD in Biochemistry and a MBA in General Management.
Dr. Ming Wang is Founder, President and CEO of Phanes Therapeutics, Inc. based in San Diego. The company focuses on drug discovery and development to treat cancer and metabolic complications. Ming was formerly Vice President and Disease Area Leader of Diabetes/Metabolism in Janssen, the pharmaceutical sector of Johnson & Johnson, with global responsibility for the diabetes portfolio (from discovery stage to phase 2). In this role, he was responsible for setting strategies for internal innovation and external partnerships, making investment decisions and building a portfolio of assets for disease treatment and prevention. Under his leadership, J&J built a strong pipeline of metabolic assets ranging from discovery stage programs to clinical assets. During his tenure at J&J, Ming’s team built many external partnerships with biotech companies and academic institutions. Ming was also the champion in formulating a strategy for NASH (non-alcoholic steatohepatitis) and other metabolic disease areas for the group. Previously, Ming was Executive Director and Head of Diabetes Research at Amgen where he headed a group of ~50 scientists located in Amgen’s headquarter (Thousand Oaks) and San Francisco, working on developing novel therapies for metabolic diseases. Before joining Amgen, Ming championed drug discovery programs in cardiovascular and metabolic diseases and managed corporate partnerships in Parke-Davis, Pfizer and Pharmacia.
Ming served on multiple advisory boards, including the Scientific Advisory Board (SAB) of Amgen Ventures. He is a frequent organizer and speaker of biotech and pharma conferences and has 59 publications and a book entitled “Metabolic Syndrome: underlying mechanisms and drug therapies” (publisher: John Wiley & Sons, Inc.). He is an Associate Editor of Frontiers in Experimental Pharmacology and Drug Discovery. He holds a PhD in Biochemistry and a MBA in General Management.
Dr. Hui Zou is an experienced and accomplished oncologist in both academia of biological research and industry of drug development. Before joining the industry, Hui was a tenured Associate Professor of the Department of Molecular Biology at UT Southwestern Medical Center. He was awarded American Cancer Society Research Scholar and Kenneth G. and Elaine A. Langone Scholar of Damon Runyon Cancer Research Foundation. His work was supported by NIH R01 and other private and public foundations. Before joining UT Southwestern Medical Center, Hui was a postdoctoral fellow in the laboratory of Marc W. Kirschner at Harvard Medical School. He was a fellow of Jane Coffin Childs Memorial Fund for Medical Research. As a graduate student, postdoctoral fellow and independent PI, Hui made important discoveries in the mechanism of sister chromatid recombination, cohesion and separation during mitosis. His discoveries generated many important publications, including 4 manuscripts published in Science or Cell as first or corresponding author.
Hui joined the industry in 2012 to translate his scientific expertise into biomedical drug discovery and development. Hui joined Phanes in 2017 and currently is the Chief Scientific Officer (CSO) and Executive VP. As the Head of R&D, Hui oversees the drug discovery and the process development teams. As his first position in the industry, Hui became Senior Director at Crown Biosciences in 2012. He led a team of 20 biologists and chemists in two integrated service projects contracted by Eli Lilly. Both projects leveraged novel cell cycle regulators to treat cancers, one of which has been advanced by Lilly into clinical development.
Hui holds a PhD degree of genetics and development from Columbia University.
Dr. Hui Zou is an experienced and accomplished oncologist in both academia of biological research and industry of drug development. Before joining the industry, Hui was a tenured Associate Professor of the Department of Molecular Biology at UT Southwestern Medical Center. He was awarded American Cancer Society Research Scholar and Kenneth G. and Elaine A. Langone Scholar of Damon Runyon Cancer Research Foundation. His work was supported by NIH R01 and other private and public foundations. Before joining UT Southwestern Medical Center, Hui was a postdoctoral fellow in the laboratory of Marc W. Kirschner at Harvard Medical School. He was a fellow of Jane Coffin Childs Memorial Fund for Medical Research. As a graduate student, postdoctoral fellow and independent PI, Hui made important discoveries in the mechanism of sister chromatid recombination, cohesion and separation during mitosis. His discoveries generated many important publications, including 4 manuscripts published in Science or Cell as first or corresponding author.
Hui joined the industry in 2012 to translate his scientific expertise into biomedical drug discovery and development. Hui joined Phanes in 2017 and currently is the Chief Scientific Officer (CSO) and Executive VP. As the Head of R&D, Hui oversees the drug discovery and the process development teams. As his first position in the industry, Hui became Senior Director at Crown Biosciences in 2012. He led a team of 20 biologists and chemists in two integrated service projects contracted by Eli Lilly. Both projects leveraged novel cell cycle regulators to treat cancers, one of which has been advanced by Lilly into clinical development.
Hui holds a PhD degree of genetics and development from Columbia University.
Dr. Rita Laeufle brings more than 18 years of experience in drug development in oncology and Immunotherapy, most recently serving as CMO at Imugene Biotech, Australia where she is responsible for their oncolytic virus and B-cell vaccine program. During her previous position at Oncolytics, she developed immunotherapy combination studies with the oncolytic virus pelareorep and anti-PD-L1 inhibitor in breast and GI cancer. Further roles included Vice president of Clinical Development & Medical Affairs at SFJ Pharmaceuticals where she developed a clinical program for a new drug substance class in colon cancer. Dr. Laeufle also worked at Genentech in South San Francisco as Senior Medical Director, U.S. Medical Affairs, gastrointestinal (GI) cancers where she led GI disease across molecules and indications. Prior moving to the United States she was Senior Medical Director and Clinical Science Leader in Oncology at Roche leading a team for the treatment of breast cancer with Avastin among other solid tumor indication fir several years. Prior that she was at Novartis roles included pharmacovigilance for oncology and drug development lead for infectious disease.
Prior joining the industry Dr. Laeufle spend 10 years in academia, she is a board-certified surgeon. She completed her general surgery residency at Buckland Hospital in Dover, England, Basel Switzerland and Ueberlingen, Germany, and was trained in surgical oncology at “Staedtisches Krankenhaus”, Singen Germany, where she focused on gastroenterological, thyroid and breast cancer. Dr. Laeufle completed medical school at Medical School Albert Ludwig University Freiburg i.Br. Germany, where she received her Ph.D. in exploring Her2 oncogenes in brain cancer. Dr. Laeufle’s work has been published in The Lancet Oncology, the European Journal of Cancer, the Journal of Hepatology and Human Pathology and she has had multiple posters presented at the American Society of Clinical Oncology (ASCO), the World Congress on Gastrointestinal Cancer (WCGC) and the European Society for Medical Oncology (ESMO).
Dr. Rita Laeufle brings more than 18 years of experience in drug development in oncology and Immunotherapy, most recently serving as CMO at Imugene Biotech, Australia where she is responsible for their oncolytic virus and B-cell vaccine program. During her previous position at Oncolytics, she developed immunotherapy combination studies with the oncolytic virus pelareorep and anti-PD-L1 inhibitor in breast and GI cancer. Further roles included Vice president of Clinical Development & Medical Affairs at SFJ Pharmaceuticals where she developed a clinical program for a new drug substance class in colon cancer. Dr. Laeufle also worked at Genentech in South San Francisco as Senior Medical Director, U.S. Medical Affairs, gastrointestinal (GI) cancers where she led GI disease across molecules and indications. Prior moving to the United States she was Senior Medical Director and Clinical Science Leader in Oncology at Roche leading a team for the treatment of breast cancer with Avastin among other solid tumor indication fir several years. Prior that she was at Novartis roles included pharmacovigilance for oncology and drug development lead for infectious disease.
Prior joining the industry Dr. Laeufle spend 10 years in academia, she is a board-certified surgeon. She completed her general surgery residency at Buckland Hospital in Dover, England, Basel Switzerland and Ueberlingen, Germany, and was trained in surgical oncology at “Staedtisches Krankenhaus”, Singen Germany, where she focused on gastroenterological, thyroid and breast cancer. Dr. Laeufle completed medical school at Medical School Albert Ludwig University Freiburg i.Br. Germany, where she received her Ph.D. in exploring Her2 oncogenes in brain cancer. Dr. Laeufle’s work has been published in The Lancet Oncology, the European Journal of Cancer, the Journal of Hepatology and Human Pathology and she has had multiple posters presented at the American Society of Clinical Oncology (ASCO), the World Congress on Gastrointestinal Cancer (WCGC) and the European Society for Medical Oncology (ESMO).
Jeremy Barton, M.D. has over 30 years of experience in all phases of oncology drug development in the pharmaceutical industry in Switzerland, UK and currently in the US. He is now working as a self-employed consultant, advising biotech companies on strategic oncology drug development
Most recent industry responsibilities in the US have included Chief Medical Officer roles at Biogen Idec, eFFECTOR Therapeutics and Mirati Therapeutics. He was also head of early Oncology Development at Pfizer (San Diego) for 5 years overseeing the transition of all Oncology compounds from research through IND to proof of concept studies.
After obtaining a Masters Degree in Physiology from Oxford University and his M.D. degree at University College Hospital Medical School in London, he trained in Internal Medicine and Clinical Oncology in the United Kingdom and practiced for 11 years in the National Health Service.
Jeremy is Board Certified in Internal Medicine and Clinical Oncology, a Member of the Royal College of Physicians, a Fellow of the Royal College of Radiologists (Clinical Oncology) and a Member of Faculty of Pharmaceutical Medicine.
Jeremy Barton, M.D. has over 30 years of experience in all phases of oncology drug development in the pharmaceutical industry in Switzerland, UK and currently in the US. He is now working as a self-employed consultant, advising biotech companies on strategic oncology drug development
Most recent industry responsibilities in the US have included Chief Medical Officer roles at Biogen Idec, eFFECTOR Therapeutics and Mirati Therapeutics. He was also head of early Oncology Development at Pfizer (San Diego) for 5 years overseeing the transition of all Oncology compounds from research through IND to proof of concept studies.
After obtaining a Masters Degree in Physiology from Oxford University and his M.D. degree at University College Hospital Medical School in London, he trained in Internal Medicine and Clinical Oncology in the United Kingdom and practiced for 11 years in the National Health Service.
Jeremy is Board Certified in Internal Medicine and Clinical Oncology, a Member of the Royal College of Physicians, a Fellow of the Royal College of Radiologists (Clinical Oncology) and a Member of Faculty of Pharmaceutical Medicine.
Chong Wang, PhD, serves as Senior Vice President of Corporate Affairs at Phanes Therapeutics. Chong leads intellectual property, legal, human resource, accounting and other aspects of the company’s operations. Chong has been with Phanes since its inception in 2016, she was previously Senior Vice President and Site Head in Phanes’ Shanghai site. Before joining Phanes, she was the head of IP department in Gan & Lee Pharmaceuticals and responsible for all domestic and international IP matters of the company. On behalf of Gan & Lee Pharmaceuticals, she won several important patent litigations against big pharma companies. Prior to Gan & Lee, Chong Wang worked in the China National Intellectual Property Office and patent attorney for many years. Chong Wang holds a PhD of Biomedical Engineering from Peking University, a bachelor’s degree of Pharmaceutical Science from Peking University Health Science Center, and a bachelor’s degree of Business Administration from Renmin University of China.
Chong Wang, PhD, serves as Senior Vice President of Corporate Affairs at Phanes Therapeutics. Chong leads intellectual property, legal, human resource, accounting and other aspects of the company’s operations. Chong has been with Phanes since its inception in 2016, she was previously Senior Vice President and Site Head in Phanes’ Shanghai site. Before joining Phanes, she was the head of IP department in Gan & Lee Pharmaceuticals and responsible for all domestic and international IP matters of the company. On behalf of Gan & Lee Pharmaceuticals, she won several important patent litigations against big pharma companies. Prior to Gan & Lee, Chong Wang worked in the China National Intellectual Property Office and patent attorney for many years. Chong Wang holds a PhD of Biomedical Engineering from Peking University, a bachelor’s degree of Pharmaceutical Science from Peking University Health Science Center, and a bachelor’s degree of Business Administration from Renmin University of China.
Chelsea Johnson, RN, joined Phanes Therapeutics as Senior Director, Clinical Science and Operations. Ms. Johnson supports clinical development and serves as the lead for the clinical operations team for advancing Phanes clinical studies and managing relationships with the clinical sites.
Ms. Johnson has over 15 years of experience in clinical development and clinical operations, from early phase to expansive global studies. She has spent over 10 years in oncology, as a clinical lead, running phase 1/2 trials in both the hematologic malignancy and solid tumor space. Prior to joining Phanes, she worked at Arch Oncology as Senior Director of Clinical Science and prior to that, she worked at Xencor serving as Director of Clinical Science and Clinical Trial Manager.
Ms. Johnson earned her B.S in Nursing from Arizona State University and worked as a registered nurse providing patient care for several years before entering into clinical development.
Chelsea Johnson, RN, joined Phanes Therapeutics as Senior Director, Clinical Science and Operations. Ms. Johnson supports clinical development and serves as the lead for the clinical operations team for advancing Phanes clinical studies and managing relationships with the clinical sites.
Ms. Johnson has over 15 years of experience in clinical development and clinical operations, from early phase to expansive global studies. She has spent over 10 years in oncology, as a clinical lead, running phase 1/2 trials in both the hematologic malignancy and solid tumor space. Prior to joining Phanes, she worked at Arch Oncology as Senior Director of Clinical Science and prior to that, she worked at Xencor serving as Director of Clinical Science and Clinical Trial Manager.
Ms. Johnson earned her B.S in Nursing from Arizona State University and worked as a registered nurse providing patient care for several years before entering into clinical development.
